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Melting - Nearest-neighbor compilation of nucleic acid hybridation

Melting computes, for a nucleic acid duplex, the enthalpy and entropy of the helix-coil transition, and then its melting temperatures. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program uses the method of nearest-neighbors. The set of thermodymanic parameters can easily be changed, for instance following an experimental breakthrough. The program is coded in ISO C and can be compiled on any operating system. Some Perl scripts are provided to show how melting can be used as a block to construct more ambitious programs.

Obtaining

Web pagehttp://www.pasteur.fr/recherche/unites/neubiomol/meltinghome.html
Source tarball http://www.pasteur.fr/recherche/unites/neubiomol/SOFTWARES/melting4_2e.tar.gz
Version 4.2 (stable) released on 2002-02-21
Licensed under The GNU General Public License, Version 2 or later.
This is a GNU package.

Documentation
User manual included and available in HTML format from http://www.pasteur.fr/recherche/unites/neubiomol/SOFTWARES/melting/melting.html
Support contacts

Help List<melting@listes.pasteur.fr> http://sympa.pasteur.fr/wws/info/melting
Developer List<melting@listes.pasteur.fr> http://sympa.pasteur.fr/wws/info/melting
Bug List<melting@listes.pasteur.fr> http://sympa.pasteur.fr/wws/info/melting

Project contacts

Maintainers
Developers
Contributors

Related information

Interfacescommand line, X Window System, web
Source languagesC, Perl
Use requirementsPerl, Perl/tk
Weak prerequisitesPerl, Perl/tk

Entry information

License verified byJanet Casey <jcasey@gnu.org> on 2001-01-31
Entry compiled byJanet Casey <jcasey@gnu.org>

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